Manipulation of Ovarian Function to Improve Reproductive Efficiency
نویسنده
چکیده
Primordial follicles comprise an oocyte surrounded by a single layer of squamous epithelial cells, called pregranulosa cells (Peters, 1978; Greenwald and Terranova, 1988). Enlargement of the oocyte and initiation of granulosa cell division mark the beginning of follicular growth (Peters, 1978). Soon after initiation of growth, the pregranulosa cells, which form the simple squamous epithelium of the primordial follicle, become cuboidal and form the follicular granulosa cell layer or membrana granulosa (Peters, 1978; Greenwald and Terranova, 1988; Zoller, 1991). The oocyte begins to synthesize and secrete the zona pellucida, which surrounds and separates the
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